| Selectionism was refuted in the 1990s. |
Evolutionary biology recognized many mechanisms besides selection, but natural selection remained an established evolutionary mechanism. |
Misleading. Criticizing adaptationism is not refuting natural selection. |
| Biology is fundamentally information-based. |
DNA stores heritable information and cells process molecular information. |
True observation, but information does not by itself imply intelligent design. |
| Biology functions through networks rather than isolated genes. |
Genes operate in complex regulatory, developmental and metabolic networks. |
True, but networks themselves evolve. |
| Mutations are not random. |
Mutation rates vary with genomic context, DNA repair, chromatin and other factors. |
Partly correct. “Random” does not mean equiprobable or causeless. |
| Stress can alter mutation processes. |
Stress responses can change mutation rates and mutation spectra. |
True, but this does not mean organisms deliberately produce the mutations they need. |
| Genomes contain mechanisms for generating variation. |
Recombination, transposable elements, gene duplication and other mechanisms generate substantial variation. |
True observation; the additional claim of design is not established. |
| Transposable elements contradict Darwinian evolution. |
Transposable elements can alter genome structure and regulation and can provide raw material for evolution. |
They are compatible with evolutionary theory, not a refutation of it. |
| Endogenous retroviruses demonstrate design. |
Some viral sequences incorporated into genomes have subsequently been co-opted for useful biological functions. |
The functional observation is real; design is an additional interpretation. |
| Genetic redundancy contradicts selection. |
Many genes are dispensable under particular experimental conditions, while redundancy and genetic robustness are widespread. |
Does not contradict selection. Fitness effects depend on environment and genetic background. |
| Natural selection cannot generate new genetic information. |
Evolutionary genetics documents novelty through duplication, divergence, recombination, regulatory evolution and de novo gene birth. |
Strongly challenged by modern evolutionary research. |
| New genetic information must already have existed in ancestral genomes. |
Some functional genes appear to arise from previously non-genic DNA. |
Not supported as a general principle. |
| Baranomes contained the information required for later biological diversity. |
Genomes certainly contain ancestral material that can be duplicated, rearranged and lost. |
The additional claim that all relevant information was originally present requires independent evidence. |
| Variation was “front-loaded” into ancestral genomes. |
Genomes contain mechanisms capable of generating variation. |
The mechanisms are real; their alleged intentional “front-loading” is an interpretation. |
| Gene duplication merely redistributes existing information. |
Duplicated genes can diverge and acquire new regulatory patterns and functions. |
Too restrictive. Duplication can provide raw material for evolutionary novelty. |
| Regulatory networks replace selection as an explanation. |
Developmental and regulatory systems constrain and bias possible evolutionary outcomes. |
Constraints and biases modify evolutionary dynamics; they do not eliminate selection. |
| Complex biological organization requires intelligent design. |
Biological systems are extraordinarily complex and functionally organized. |
Complexity is an observation, not by itself evidence for a designer. |
| Darwinism is an “atheists' religion.” |
Evolutionary biology is a scientific framework used by people with many different philosophical and religious beliefs. |
Rhetoric, not a scientific refutation. |
| Modern molecular biology has falsified Darwinism. |
Modern molecular biology has greatly expanded evolutionary theory and revealed additional mechanisms of variation and inheritance. |
The central claim is not demonstrated. |